Fresh analysis suggests that individuals who discontinue popular slimming jabs like Mounjaro or Wegovy can put back on reduced body mass far faster than those who stop traditional diet and exercise plans.
Findings released in a major medical journal demonstrates that while overweight people frequently drop about a fifth of their body weight while using the jabs, the weight returns at an average rate of 0.8 kg per month after stopping.
"Individuals purchasing these drugs need to be cognizant of the danger of fast rebound weight gain when the therapy concludes," cautioned researcher Dr. Susan Jebb.
This pace of recovery implies a reversion to original weight in about one and a half years.
Comparing Treatments
The analysis, which reviewed 37 of trials involving over 9,000 of patients, contrasted the effects of GLP-1 agonists with conventional dieting.
Researchers emphasize that people who shed pounds through diet and exercise typically have a less rapid creep back—approximately 100 grams monthly—post-intervention.
The Reason for the Rapid Regain
Nutrition scientists propose the way of the injections explains the amplified weight return.
GLP-1 drugs copy a natural hormone called glucagon-like peptide-1, which moderates hunger.
"Artificially providing GLP-1 concentrations far above than normal might result in the body to produce less of its own natural hormone, and may also lessen sensitivity to its effects," noted Dr. Adam Collins, a dietetics researcher.
"Discontinuation of this medication means appetite is uncontrolled, making overeating much more probable."
A Chronic Issue?
Medical guidelines suggest the injections for people with obesity-related health risks, accompanied by recommended diet and exercise modifications.
A number of clinicians say that, considering the likelihood of weight regain, the treatment should be considered ongoing.
This opinion is supported by pharmaceutical companies, who say that the results "underscore the persistent character of excess weight," akin to managing diseases like diabetes.
Patient Experiences
People who have stopped the medication explain a intense resurgence of hunger.
"It felt as if something that goes on and you become starving," described a patient.
The struggle is worsened if users have not adopted sustainable lifestyle or habit changes during treatment.
Significant Adoption
Figures indicate that millions of adults in the UK have tried these injections in the past year, with desire remaining high.
- Use is higher among women compared to men.
- The 40s and 50s age group shows the greatest usage rates.
- Many access the medications through private healthcare rather than the NHS.
In conclusion, researchers stress that while GLP-1 drugs are powerful tools for shedding pounds, they are not a magic solution and lasting health benefits likely depends on combined behavioural changes.
